Potential Joint Effect of the SNP rs3749474T and SNP rs4864548AAlleles of the CLOCK Gene on Nutritional Status and Chronotype in Young University Students

Authors

DOI:

https://doi.org/10.14482/sun.37.1.613.2

Keywords:

CLOCK gene, obesity, chronotype

Abstract

Objective: To compare the nutritional status, chronotype and eating behavior of a subject who simultaneously has the rs3749474T and rs4864548A polymorphisms to groups of subjects who have only one of these polymorphisms.

Methods: The presence of the polymorphisms was established by PCR. BMI, cardiovascular risk, and fat percentage were determined as described by Durnin and Womersley and the Siri equation. The TFEQ-P19 questionnaire (adapted to the Chilean population) and the Horne-Ostberg questionnaire were applied.

Results: The subject with both polymorphisms presented obesity, cardiovascular risk, and late-night chronotype. Its scores on the dimensions of uncontrolled feeding and emotional feeding were low, and its score for cognitive restriction was the highest.

Conclusions: The presence of the TA haplotype (rs3749474; rs4864548A) would increase the possibility of having a late-night type chronotype, risk of obesity, and cardiovascular risk associated with waist centimeters.

Author Biographies

  • Carolina Pino-astorga, Facultad de Salud. Escuela de Nutrición y Dietética. Universidad Bernardo O´Higgins. Santiago, Chile.

    Facultad de Ciencias de la Salud, Escuela de Nutrición y Dietética, Universidad Bernardo O´Higgins. Santiago (Chile)

  • Angel gerardo Roco-Videla, Universidad Católica de la Santísima Concepción, Concepción Chile.Universidad Bernardo O'Higgins, Chile

    Facultad de Ciencias de la Salud, Programa Magíster en Ciencias químico-biológicas, Universidad Bernardo O´Higgins. Santiago (Chile).
    Facultad de Ingeniería, Universidad Católica de la Santísima Concepción. Concepción (Chile)

  • Macarena Valladares Vega, Departamento de Ciencias Química y Biológicas Facultad de Salud, Universidad Bernardo O´Higgins, Chile

    Centro Integrativo de Biología y Química Aplicada (CIBQA), Universidad Bernardo O´Higgins. Santiago (Chile).

Downloads

Published

2022-01-19

Issue

Section

ORIGINAL ARTICLE

How to Cite

Potential Joint Effect of the SNP rs3749474T and SNP rs4864548AAlleles of the CLOCK Gene on Nutritional Status and Chronotype in Young University Students. (2022). SCIENTIFIC JOURNAL SALUD UNINORTE, 37(1), 11-21. https://doi.org/10.14482/sun.37.1.613.2

Similar Articles

1-10 of 329

You may also start an advanced similarity search for this article.