Therapies that Have Shown Efficacy Against COVID-19: A Narrative Review

Authors

  • Luis Gustavo Celis Regalado University of La Sabana, Colomabia
  • Constanza Neri Morales University of La Sabana, Colomabia
  • Felipe Alejandro Ilelaty Urbano University of La Sabana, Colomabia
  • José David Cardona Ortegón University Hospital Fundación Santa Fe de Bogotá, Colombia
  • Jorge Luis Cortés Jiménez University of La Sabana, Colomabia
  • María Fernanda Maza Malave University of La Sabana, Colomabia
  • Emma Balcázar Muñoz
  • José Sanabria Vanegas University of La Sabana, Colomabia

DOI:

https://doi.org/10.14482/sun.39.02.305.428

Keywords:

COVID-19, medications, variants, treatment, infection, mortality

Abstract

Background: The new coronavirus disease has accelerated the development of therapeutic guidelines for patients depending on their degree of severity. To date, many drugs have been studied. However, with the passing of time, a few therapeutic groups have been effective and have evidenced a reduction in patient mortality and morbidity.

Methods: A search and identification of articles published in the following electronic databases was carried out: PubMed, Clinical Key, Web of Science and Scopus for their analysis and selection in English and Spanish. The literature research emphasizes the search for current guidelines on the treatment of COVID-19, including all degrees of severity, seeking the effectiveness of the medication.

Results: For each drug listed, its pharmacodynamics, pharmacokinetics, and general recommendations for use in adult patients with COVID-19 are described.

Conclusions: During the COVID-19 pandemic, numerous groups of drugs have been studied, however, only a select group have been shown to have a role in the treatment of the disease. The literature and guidelines support the use of these managements.

Author Biographies

Luis Gustavo Celis Regalado, University of La Sabana, Colomabia

  • Research Biologist, Specialization Course in Immunology, Specialist in Immunology, Specialist in Bioethics, Specialist in Foresight and Organizational Strategy, master’s in biology with emphasis in Human Genetics
  • Email: luis.celis@unisabana.edu.co

Constanza Neri Morales , University of La Sabana, Colomabia

  • Medical Intern - University of La Sabana
  • Email: constanzane@unisabana.edu.co
  • ORCID: https://orcid.org/0000-0002-1785-0832
  • CVLAC:https://scienti.minciencias.gov.co/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0001753245
  • University of La Sabana

Felipe Alejandro Ilelaty Urbano, University of La Sabana, Colomabia

  • MD University of La Sabana
  • Email: felipeilelaty@gmail.com
  • ORCID: https://orcid.org/0000-0002-1123-537X
  • CVLAC: https://scienti.minciencias.gov.co/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0001886887
  • University of La Sabana

José David Cardona Ortegón, University Hospital Fundación Santa Fe de Bogotá, Colombia

  • MD University of La Sabana

Jorge Luis Cortés Jiménez, University of La Sabana, Colomabia

  • MD University of La Sabana
  • Email: jorgecoji@unisabana.edu.co
  • ORCID: https://orcid.org/0000-0003-2823-9745
  • CVLAC: https://scienti.minciencias.gov.co/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0001885921
  • University of La Sabana

María Fernanda Maza Malave, University of La Sabana, Colomabia

  • MD University of La Sabana
  • Email: mariamazma@unisabana.edu.co
  • ORCID: 0000-0003-1994-6464
  • CVLAC:https://scienti.minciencias.gov.co/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0001901538

 

José Sanabria Vanegas, University of La Sabana, Colomabia

  • MD University of La Sabana
  • Email: emmabalcazar9@gmail.com
  • ORCID: 0000-0002-3271-9461
  • CVLAC:https://scienti.minciencias.gov.co/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0002021987

Published

2023-09-18

How to Cite

Celis Regalado, L. G. ., Neri Morales , C., Ilelaty Urbano, F. A., Cardona Ortegón, J. D. ., Cortés Jiménez, J. L., Maza Malave, M. F. ., Balcázar Muñoz, E. ., & Sanabria Vanegas, J. (2023). Therapies that Have Shown Efficacy Against COVID-19: A Narrative Review. Salud Uninorte, 39(2), 765–791. https://doi.org/10.14482/sun.39.02.305.428

Issue

Section

Review Article

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