Association Between Cold Exposure and Asthma: Systematic Review and meta-analysis, 1965-2015

Autores/as

  • Germán Zuluaga Ramírez Universidad del Rosario
  • Ivan Sarmientp Combariza
  • Juan Pimentel González
  • Neil Ardersson

DOI:

https://doi.org/10.14482/sun.36.1.616,238%20

Palabras clave:

Salud respiratoria, asma, factores culturales, medicina tradicional, epidemiología intercultural

Resumen

Objectives: to conduct a systematic review and a meta-analysis of observational and expe- rimental studies that explore the relation between asthma and cold exposure. Materials and methods: systematic review of experimental and observational studies pu- blished up to August 2015 in Pubmed, Embase and Lilacs. Two researchers selected studies that measured the occurrence of asthma in individuals exposed to different environmen- tal temperatures. A meta-analysis used RevMan 5.3’s random effects model to calculate a summary weighted Odds Ratio with 95% confidence intervals, and a sensitivity analysis identified the influence of each study. Subsequent subgroup analyses identified summary measures by type of cold exposure and study design. Additional analysis measured hetero- geneity and risk of bias. Results: we found 86 studies measuring the relation between cold exposure and asthma. We included 11.6% (10/86) of the studies in the meta-analysis and found an association between cold exposure and asthma with all the studies (ORw 2.0 95%CI 1.28-3.14), with the subgroup of experimental studies (ORw 3.8 IC95% 1.70-8.86), and with cold environmental air (ORw 1.59 IC95% 1.10-2.30). The studies had high risk of bias and statistical heteroge- neity [I2 : 63.1% (27%-81.4%)]. Conclusions: the results support the hypothesis of an association between asthma and cold exposure. This study encourages to explore the concepts proposed by traditional medi- cine to establish its benefits on prevention and care of respiratory diseases, such as asthma.

Biografía del autor/a

Ivan Sarmientp Combariza

Candidato a doctor en Medicina Familiar. Department of Family Medicine, McGillUniversity. ivan.sarmiento@mail.mcgill.ca. Orcid: 0000-0003-2871-1464. http://scienti.colciencias.gov.co:8081/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0001016156

Juan Pimentel González

Candidato a doctor en Medicina Familiar. Department of Family Medicine, McGillUniversity. juan.pimentel@mail.mcgill.ca. Orcid: 0000-0002-6842-3064. http://scienti.colciencias.gov.co:8081/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0001474877

Neil Ardersson

Director, CIET-PRAM, Department of Family Medicine, McGill University. Orcid: 0000-0003-1121-6918

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Publicado

2020-11-27

Cómo citar

Zuluaga Ramírez, G., Sarmientp Combariza, I., Pimentel González, J., & Ardersson, N. (2020). Association Between Cold Exposure and Asthma: Systematic Review and meta-analysis, 1965-2015. Revista Científica Salud Uninorte, 36(1). https://doi.org/10.14482/sun.36.1.616,238

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